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CHEM120 Freshman Organic Chemistry YALE (37 VIDEOS)

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YALE

CHEM125 (Fall 2008)
Instructor:
J. Michael McBride

Level
Undergraduate



J. Michael McBride is the Richard M. Colgate Professor of Chemistry at Yale University.

Course Description

This is the first semester in a two-semester introductory course focused on current theories of structure and mechanism in organic chemistry, their historical development, and their basis in experimental observation. The course is open to freshmen with excellent preparation in chemistry and physics, and it aims to develop both taste for original science and intellectual skills necessary for creative research.

 

About Your Professor

J. Michael McBride is the Richard M. Colgate Professor of Chemistry at Yale University. After undergraduate work at the College of Wooster and Harvard College Professor McBride earned a Ph.D. in physical organic chemistry at Harvard University. He joined the Yale Chemistry faculty in 1966, where he studies crystal growth and reactions in organic solids. His awards include the Prelog Medal, the Nobel Laureate Signature Award in Graduate Education, and the Catalyst Award of the Chemical Manufacturers Association for undergraduate education. Further details on his life, research, and teaching are available in Crystal Growth & Design, 2005, 5 (6), pp 2022–2035.

 

 

Course Resources

Freshman Organic Chemistry
Syllabus
Class sessions
Downloads
 

Course Video Lectures, Audio Lectures, Lecture Notes, & Transcripts

1. How Do You Know?
2. Force Laws, Lewis Structures and Resonance
3. Double Minima, Earnshaw's Theorem, and Plum-Puddings
4. Coping with Smallness and Scanning Probe Microscopy
5. X-Ray Diffraction
6. Seeing Bonds by Electron Difference Density
7. Quantum Mechanical Kinetic Energy
8. One-Dimensional Wave Functions
9. Chladni Figures and One-Electron Atoms
10. Reality and the Orbital Approximation
Midterm Exam 1
11. Orbital Correction and Plum-Pudding Molecules
12. Overlap and Atom-Pair Bonds
13. Overlap and Energy-Match
14. Checking Hybridization Theory with XH3
15. Chemical Reactivity: SOMO, HOMO, and LUMO
16. Recognizing Functional Groups
17. Reaction Analogies and Carbonyl Reactivity
18. Amide, Carboxylic Acid and Alkyl Lithium
19. Oxygen and the Chemical Revolution (Beginning to 1789)
Midterm Exam 2
20. Rise of the Atomic Theory (1790-1805)
21. Berzelius to Liebig and Wöhler (1805-1832)
22. Radical and Type Theories (1832-1850)
23. Valence Theory and Constitutional Structure (1858)
24. Determining Chemical Structure by Isomer Counting (1869)
25. Models in 3D Space (1869-1877); Optical Isomers
26. Van't Hoff's Tetrahedral Carbon and Chirality
27. Communicating Molecular Structure in Diagrams and Words
28. Stereochemical Nomenclature; Racemization and Resolution
29. Preparing Single Enantiomers and the Mechanism of Optical Rotation
Midterm Exam 3
30. Esomeprazole as an Example of Drug Testing and Usage
31. Preparing Single Enantiomers and Conformational Energy
32. Stereotopicity and Baeyer Strain Theory
33. Conformational Energy and Molecular Mechanics
34. Sharpless Oxidation Catalysts and the Conformation of Cycloalkanes
35. Understanding Molecular Structure and Energy through Standard Bonds
36. Bond Energies, the Boltzmann Factor and Entropy
37. Potential Energy Surfaces, Transition State Theory and Reaction Mechanism
Final Exam


Course Downloads

The file below contains all of the course pages from this course and may be downloaded for offline use. The file is offered in .zip format; you must have access to a suitable decompression application to unzip the contents before use. After decompressing the file, please click "start.html" to launch.


[ download all course pages ] - size 9.1 MB - file type application/zip

Audio and video files of Open Yale Courses may be downloaded in three ways: iTunes U and RSS for multiple downloads, or the links below for individual files.

To download all tracks from iTunes U, click the "Get Tracks" button on any course page in the iTunes U interface. If the download is interrupted, click "Resume" to continue the download process. You must have Apple's iTunes software installed on your computer to download from iTunes U.

To download all media files directly from this page, click an RSS icon below and set your Internet browser to subscribe using an appropriate podcatching application. Alternatively, right-click on an icon (Mac users: control-click), copy the link, and paste it directly into your preferred podcatching application.

 

To download individual media files from the course, please click the links in the Class Sessions section below. Apple QuickTime 7.2 or higher is required to view the videos, while the mp3 files will play in any mp3-compatible device/player.

 

 

 
  1. How Do You Know? [ high bandwidth ]    [ medium bandwidth ] [ mp3 ]
  2. Force Laws, Lewis Structures and Resonance [ high bandwidth ]    [ medium bandwidth ] [ mp3 ]
  3. Double Minima, Earnshaw's Theore... [ high bandwidth ]    [ medium bandwidth ] [ mp3 ]
  4. Coping with Smallness and Scanning Probe... [ high bandwidth ]    [ medium bandwidth ] [ mp3 ]
  5. X-Ray Diffraction [ high bandwidth ]    [ medium bandwidth ] [ mp3 ]
  6. Seeing Bonds by Electron Difference Density [ high bandwidth ]    [ medium bandwidth ] [ mp3 ]
  7. Quantum Mechanical Kinetic Energy [ high bandwidth ]    [ medium bandwidth ] [ mp3 ]
  8. One-Dimensional Wave Functions [ high bandwidth ]    [ medium bandwidth ] [ mp3 ]
  9. Chladni Figures and One-Electron Atoms [ high bandwidth ]    [ medium bandwidth ] [ mp3 ]
  10. Reality and the Orbital Approximation [ high bandwidth ]    [ medium bandwidth ] [ mp3 ]
  11. Orbital Correction and Plum-Pudding Molecules [ high bandwidth ]    [ medium bandwidth ] [ mp3 ]
  12. Overlap and Atom-Pair Bonds [ high bandwidth ]    [ medium bandwidth ] [ mp3 ]
  13. Overlap and Energy-Match [ high bandwidth ]    [ medium bandwidth ] [ mp3 ]
  14. Checking Hybridization Theory with XH3 [ high bandwidth ]    [ medium bandwidth ] [ mp3 ]
  15. Chemical Reactivity: SOMO, HOMO... [ high bandwidth ]    [ medium bandwidth ] [ mp3 ]
  16. Recognizing Functional Groups [ high bandwidth ]    [ medium bandwidth ] [ mp3 ]
  17. Reaction Analogies and Carbonyl Reactivity [ high bandwidth ]    [ medium bandwidth ] [ mp3 ]
  18. Amide, Carboxylic Acid and Alkyl Lithium [ high bandwidth ]    [ medium bandwidth ] [ mp3 ]
  19. Oxygen and the Chemical Revolution... [ high bandwidth ]    [ medium bandwidth ] [ mp3 ]
  20. Rise of the Atomic Theory (1790-1805) [ high bandwidth ]    [ medium bandwidth ] [ mp3 ]
  21. Berzelius to Liebig and Wöhler... [ high bandwidth ]    [ medium bandwidth ] [ mp3 ]
  22. Radical and Type Theories (1832-1850) [ high bandwidth ]    [ medium bandwidth ] [ mp3 ]
  23. Valence Theory and Constitutional Structure... [ high bandwidth ]    [ medium bandwidth ] [ mp3 ]
  24. Determining Chemical Structure by Isomer... [ high bandwidth ]    [ medium bandwidth ] [ mp3 ]
  25. Models in 3-D Space (1869-1877); Optical... [ high bandwidth ]    [ medium bandwidth ] [ mp3 ]
  26. Van't Hoff's Tetrahedral Carbon and Chirality [ high bandwidth ]    [ medium bandwidth ] [ mp3 ]
  27. Communicating Molecular Structure... [ high bandwidth ]    [ medium bandwidth ] [ mp3 ]
  28. Stereochemical Nomenclature... [ high bandwidth ]    [ medium bandwidth ] [ mp3 ]
  29. Preparing Single Enantiomers and... [ high bandwidth ]    [ medium bandwidth ] [ mp3 ]
  30. Esomeprazole as an Example of Drug... [ high bandwidth ]    [ medium bandwidth ] [ mp3 ]
  31. Preparing Single Enantiomers and... [ high bandwidth ]    [ medium bandwidth ] [ mp3 ]
  32. Stereotopicity and Baeyer Strain... [ high bandwidth ]    [ medium bandwidth ] [ mp3 ]
  33. Conformational Energy and... [ high bandwidth ]    [ medium bandwidth ] [ mp3 ]
  34. Sharpless Oxidation Catalysts... [ high bandwidth ]    [ medium bandwidth ] [ mp3 ]
  35. Understanding Molecular Structure... [ high bandwidth ]    [ medium bandwidth ] [ mp3 ]
  36. Bond Energies, the Boltzmann Factor... [ high bandwidth ]    [ medium bandwidth ] [ mp3 ]
  37. Potential Energy Surfaces... [ high bandwidth ]    [ medium bandwidth ] [ mp3 ]

 

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Copyright 2007, by the Contributing Authors. Cite/attribute Resource. administrator. (2009, November 20). CHEM120 Freshman Organic Chemistry YALE (37 VIDEOS). Retrieved March 11, 2010, from Free University Courses OCW Courses OpenCourseWare Freeversity Foundation Web site: http://freeversity.org/science-and-mathematics/chemistry/chem120-freshman-organic-chemistry-yale-37-videos. This work is licensed under a Creative Commons License Creative Commons License